Transforming health through digital technology

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With our digital health research, we are charting a course toward innovative and secure digital health technologies with the capacity to improve people’s health.

Bénédicte Poumarède

Head of Digital Health Program — CEA-List

A deep understanding of the key technology issues

Digital transformation provides a real opportunity to develop foundational, real-world solutions that deliver improvements to the French healthcare system. CEA-List has expertise in technologies that are vital to the healthcare sector, including responsible AI, cybersecurity, the design of reliable and secure software, trusted networks, secure data processing, digital twins, and instrumentation. This deep knowledge of healthcare tech challenges makes CEA-List a partner for manufacturers, hospitals, and research institutes.

Assisted diagnostics

The goal is to develop optical and/or ultrasound imaging systems that can be used for early diagnosis:

  • Portable imagers with high acquisition rates provide real time flow analysis of visible images (implementation of near-sensor embedded AI technologies) for diagnostics.
  • Transcranial ultrasound imaging systems made more efficient by simulating the propagation of ultrasound waves in complex and solid media (implementation of technologies used in non-destructive testing). One specific use case is the early detection of strokes.

Related project: H2020 Attract EchoBrain

 

Tools and platforms used

Two lines of research are being pursued at CEA-List:

  • The development of tools for the automatic extraction and analysis of heterogeneous data (images, text, biological analyses, spectrometric measurements, etc.) associated with explainable artificial intelligence, with the aim of making recommendations to healthcare professionals to facilitate diagnosis.
  • The development of diagnostic tests to ensure better patient management.

Implementations

  • Image analysis coupled with decision support (wound monitoring, dental disease classification, mole characterization, etc.).
  • Detection of a specific Covid signature in exhaled breath using data processing and analysis (ANR COVInose project).

Related projects: H2020 DeepHealth – ANR COVInose project

 

Tools and platforms used

Assisted therapy

Radiotherapy, which can deliver locally controlled doses of radiation to affected tissue, is considered a precision technique for treating cancer. CEA-List’s DOSEO platform provides various high-performance software tools and equipment to develop solutions for measuring and optimizing the doses delivered to patients and personalizing treatment plans.

Related projects:

  • Industrial: with startup RT3C
  • Institutional: ELISA (2020-2022), H2020 HARMONIC (2019-2024)

Tools and platforms used

  • DOSEO platform
  • PHOEBE (radiation–matter interaction simulation)

 

Visit the website DOSEO

Innovative therapies, in particular high-intensity focused ultrasound (HIFU), are about to revolutionize therapeutic treatments. CEA-List’s simulation techniques can enhance these new treatments:

  • Embedded simulation to create individualized treatment protocols in real time for optimized, personalized HIFU treatments.
  • Optimization of parameters for personalized treatment.
  • Decision support during treatment.

Related project: ANR Saturn 2015-2019

 

Tools and platforms used

Patient monitoring

CEA-List is developing solutions to monitor a patient’s physical health remotely and in real time. The objectives are to be able to detect and diagnose any deterioration in a patient’s condition as early as possible and make adjustments to treatment protocols.

To ensure the large-scale adoption of these solutions, we are focusing on using easily accessible measurement technologies that are already widely available. A major challenge for remote patient monitoring is providing reliable, secure, and safe solutions that comply with data privacy laws and new regulations.

 

Tools and platforms used

CEA-List is developing solutions to leverage the data in patient medical records to monitor patient health remotely after a hospital stay.

The information extracted can make in-home patient monitoring simpler and more reliable and is easier to share with stakeholders within the hospital and, possibly, with the national health insurance administration and the Health Data Hub.

Related project: e-Meuse

 

Tools and platforms used

  • LIMA/CLIMA platform (textual information extraction)

Helping people with disabilities

CEA-List is exploring several software tools and hardware devices for personal assistance applications:

  • A smart white cane, based on SigmaFusion technology, with sensors coupled with an audio feedback system, gives the visually impaired 3D spatial awareness of their environment so they can “hear” obstacles.
  • Embedded environmental perception algorithms.
  • Assisted living tools with haptic and/or audio feedback technologies that support people with cognitive or motor disabilities and, more generally, anyone who requires monitoring.

Related project: H2020 INSPEX (2017-2019); Cplay (ANR)

 

Tools and platforms used

  • AI platform

Two use cases are being explored at CEA-List:

  • An exoskeleton used for functional rehabilitation.
  • A versatile multisensory digital companion to provide patients with better information during their hospital stay and support improved wellness.

Tools and platforms used

Organizational innovation

CEA-List is working on a functional digital twin of hospitals that can be used to organize and optimize internal flows based on real-world constraints.

 

Tools and platforms used

CEA-List is developing solutions to support better training for healthcare personnel. These include mixed reality surgical training systems that leverage digital content and haptic interfaces to simulate different surgical procedures and force feedback systems to help train physical therapists. These realistic simulation tools can also be used to train future doctors.

Joint project with digital anatomical solutions provider Anatoscope (OTANDEM project)

 

Tools and platforms used

Our implementations – Our products

Immersive physical maxillofacial surgical training platform.

Simulators, one designed to assist in the diagnosis of cruciate ligament rupture and the other in the reduction of mandibular dislocation.

Software developed to quantify the complexity of a radiotherapy treatment plan to assess the suitability of systematic early-stage quality control.

See also